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PEM report number 4. Ciprofloxacin by William Inman; Kiyoshi Kubota; Gillian Pearce; Lynda Wilton is a Medicine article available to read on EtoBox.

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## Abstract The fluoroquinolone antibiotic ciprofloxacin has been studied by Prescription‐Event Monitoring (PEM) in 11,477 patients who had received prescriptions from general practitioners in England between November 1988 and January 1989. There were about 50% more females in the series than males and the average ages were 53.2 and 55.5 years respectively. Chest and urinary infections were the most common indications. Forty‐five per cent of the patients used 500 mg daily and 42% 1000 mg daily. Ciprofloxacin was said to have been effective in 90.3% of patients. The events were compared with those reported in 25 other studies in order to obtain some impression of the background rates in a population of more than a quarter of a million patients monitored by PEM. The events most frequently reported were related to the infections that were being treated and the most common side‐effects were those affecting the gastrointestinal system. There were three definite and one doubtful case of photosensitivy. Among the psychiatric events, only depression and malaise or lassitude occurred at a rate which exceeded one per 1000 patients during the first 13 weeks of follow‐up. Fourteen patients suf

Who reads PEM report number 4. Ciprofloxacin?

Author

William Inman; Kiyoshi Kubota; Gillian Pearce; Lynda Wilton

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-8569)

Published

1993

Language

SU

Field

Medicine (Health Sciences)