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Drug Distribution Models for CNS by Walaa Yousef is a document available to read on EtoBox.
What is Drug Distribution Models for CNS about?
The document discusses in vitro, in vivo and in silico models for studying drug distribution into the brain. It summarizes different techniques like microdialysis, PET imaging and PBPK modeling that provide measurements of total and unbound drug concentrations in blood and brain to understand factors influencing brain penetration. The techniques aim to predict likelihood of drugs successfully reaching targets in the central nervous system.
- Author
- Walaa Yousef
- Language
- EN