Can I read Prognostic Significance of Capsular Invasion and Capsular Penetration in Patients with Clinically Localized Prostate Cancer Undergoing Radical Prostatectomy on EtoBox?

Prognostic Significance of Capsular Invasion and Capsular Penetration in Patients with Clinically Localized Prostate Cancer Undergoing Radical Prostatectomy by Dr Matthias Theiss; Manfred P. Wirth; Andreas Manseck; Hubert G. W. Frohmüller is a Medicine article available to read on EtoBox.

What is Prognostic Significance of Capsular Invasion and Capsular Penetration in Patients with Clinically Localized Prostate Cancer Undergoing Radical Prostatectomy about?

## Abstract One hundred thirty patients with an observed follow‐up of more than 10 years after radical prostatectomy were restaged with regard to local extent of the tumor in relation to the prostate capsule. Of 112 patients with surgically staged negative pelvic lymph nodes, 62 had a tumor‐free prostate capsule, 24 had capsular invasion without penetration, and 26 had tumors extending through the capsule of the prostate. Observed overall and disease‐free 10‐year‐survival rates were 79% and 69.4%, respectively, in patients with absence of capsular involvement and 70.8% and 66.7%, respectively, in patients with capsular invasion alone. In patients with capsular penetration, however, the survival rates significantly decreased to 57.7% (__P__ = 0.018) and to 38.5 (__P__ = 0.017), respectively. The overall progression rate was found to be significantly higher in patients with tumors extending through the prostatic capsule (46.2%), as compared to those with absence of capsular involvement (21%; __P__ = 0.014) as well as to those with capsular invasion alone without penetration (25%; __P__ = 0.034). Thus, in contrast to capsular invasion alone, capsular penetration means a poor prognosti

Who reads Prognostic Significance of Capsular Invasion and Capsular Penetration in Patients with Clinically Localized Prostate Cancer Undergoing Radical Prostatectomy?

Author

Dr Matthias Theiss; Manfred P. Wirth; Andreas Manseck; Hubert G. W. Frohmüller

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0270-4137)

Published

1995

Language

EN

Field

Medicine (Health Sciences)