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Can I read Changes in lymphocyte subpopulations and CD3+/DR + expression in sepsis on EtoBox?
Changes in lymphocyte subpopulations and CD3+/DR + expression in sepsis by M. Holub; Z. Klučková; B. Beneda; J. Hobstová; I. Hužička; J. Pražák; A. Lobovská is a Medicine article available to read on EtoBox.
What is Changes in lymphocyte subpopulations and CD3+/DR + expression in sepsis about?
## Objective: To detect lymphocyte subpopulations and cd3+/dr + expression in sepsis. ## Methods: In a prospective clinical study we evaluated subpopulations of lymphocytes and percentage of cd3+/hla-dr+ lymphocytes using two-color flow cytometry in 40 patients with sepsis and compared them with 34 healthy adults. ## Results: Septic patients, when compared with healthy controls, have significantly lower percentage and absolute numbers of total t lymphocytes and cd4 t lymphocytes (p < 0.01). absolute numbers of cd8 t lymphocytes, nk cells, cd3+/dr + lymphocytes and cd4/cd8 ratio were also decreased (p < 0.01). the percentage of b lymphocytes was increased (p < 0.01). ## Conclusion: Our results are in agreement with previous findings in patients with sepsis after major surgery or trauma. the decreases in the percentage and absolute numbers of circulating lymphocyte subsets in non-surgical sepsis could represent a general reaction to stress. increased percentage of b lymphocytes is most probably related to the bacterial etiology of the disease.
Who reads Changes in lymphocyte subpopulations and CD3+/DR + expression in sepsis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- M. Holub; Z. Klučková; B. Beneda; J. Hobstová; I. Hužička; J. Pražák; A. Lobovská
- Publisher
- John Wiley and Sons; Elsevier ; Elsevier Limited; Elsevier BV; Test accounts (ISSN 1198-743X)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)