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Amplification of IS6110 sequence for detection of Mycobacterium tuberculosis complex in HIV-negative patients with fever of unknown origin (FUO) and evidence of extrapulmonary disease by K. Ritis; D. Tzoanopoulos; M. Speletas; E. Papadopoulos; K. Arvanitidis; S. Kartali; P. Sideras is a Medicine article available to read on EtoBox.
What is Amplification of IS6110 sequence for detection of Mycobacterium tuberculosis complex in HIV-negative patients with fever of unknown origin (FUO) and evidence of extrapulmonary disease about?
**Abstract.** Ritis K, Tzoanopoulos D, Speletas M, Papadopoulos E, Arvanitidis K, Kartali S, Sideras P (Democritus University of Thrace, Regional Hospital of Alexandroupolis, Alexandroupolis, Greece, and University of Umeå, Umeå, Sweden). Amplification of IS6110 sequence for detection of __M. tuberculosis__ complex in HIV‐negative patients with fever of unknown origin (FUO) and evidence of extrapulmonary disease. __J Intern Med__ 2000; **248:** 415–424. **Objectives.** Extrapulmonary tuberculosis (TB) constitutes the main cause of classic fever of unknown origin (FUO) in many populations. The aim of this study was to improve the diagnostic field of the disease using a nested polymerase chain reaction (PCR) assay, specific for the IS6110 insertion element of __Mycobacterium tuberculosis__ complex, in order to achieve a more timely diagnosis and treatment. **Setting.** Twenty‐four, HIV‐negative classic FUO patients who were admitted to the Regional Hospital of Alexandroupolis between April 1997 and July 1999. **Subjects and design.** The above patients were considered as putative extrapulmonary TB after 3 weeks of in‐patient investigation and underwent exhaustive examination for diag
Who reads Amplification of IS6110 sequence for detection of Mycobacterium tuberculosis complex in HIV-negative patients with fever of unknown origin (FUO) and evidence of extrapulmonary disease?
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- Author
- K. Ritis; D. Tzoanopoulos; M. Speletas; E. Papadopoulos; K. Arvanitidis; S. Kartali; P. Sideras
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)