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Automatic detection and quantification of hand movements toward development of an objective assessment of tremor and bradykinesia in Parkinson's disease by Yan Pang; Jake Christenson; Feng Jiang; Tim Lei; Remy Rhoades; Drew Kern; John A. Thompson; Chao Liu is a Neuroscience article available to read on EtoBox.

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## Background: Classification of parkinsonian symptoms, including tremor and bradykinesia, require the application of validated clinical rating scales which are inherently subjective. in this study, we assessed an objective measure of parkinsonian symptomology using automated analysis of hand gestures. ## New method: We constructed and evaluated a hand and finger motion capture apparatus and analysis pipeline that recorded hand/finger motion of control subjects and patients with parkinson's disease. the detailed three-dimensional (3d) motion features of each finger joint was extracted by using discrete wavelet transform (dwt). the severity of tremor for each finger joint was quantitated by analyzing the motion changes in the frequency domain on four types of motion from five patients and twenty-two control subjects. ## Results: The proposed approach could distinguish the behavior of patients with parkinson's disease and control subjects by analyzing the detailed motion features of their hands/fingers. ## Comparison with existing methods: Previously established methods to quantitate finger movement dynamics focus on speed and amplitude. in contrast, our approach measures unsupervise

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Author

Yan Pang; Jake Christenson; Feng Jiang; Tim Lei; Remy Rhoades; Drew Kern; John A. Thompson; Chao Liu

Published

2020

Language

EN

Field

Neuroscience (Life Sciences)