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Differential Response to Three Antidepressants in Patients with Major Depressive Episode Who Suffered Covid-19-Related Trauma by Ginevra Lombardozzi; Georgios D. Kotzalidis; Sergio De Filippis; Marta Matrone; Emanuela Amici; Giada Trovini; Filippo Perrini; Alessandro Di Giovanni; Valeria Giovanetti is a Neuroscience article available to read on EtoBox.
What is Differential Response to Three Antidepressants in Patients with Major Depressive Episode Who Suffered Covid-19-Related Trauma about?
## Background The Covid 19 pandemic might have impacted response to drug treatment in major depressive episode (MDE). We compared responses to three different antidepressant drugs, __i.e.__, vortioxetine, sertraline, and trazodone, in outpatients with MDE during Major Depressive Disorder (MDD), Bipolar Disorder (BD), or schizophrenia and related psychoses (SSOPDs) during two time periods, __i.e.__, before and after suffering Covid-19-related trauma. ## Methods We conducted an observational study on clinically stabilised for at least 6 months outpatients with MDE during the course of MDD (N=58), BD (N=33), or SSOPDs (N=51). Patients, whose baseline assessments of Montgomery-Åsberg Rating Scale (MADRS), Hamilton Anxiety Rating Scale (Ham-A), Brief Psychiatric Rating Scale (BPRS), Visual Analogue Scale for Craving (VAS-crav) and World Health Organization Quality of Life, Brief version (WHOQOL-BREF) were available, were recruited at the time they suffered Covid-19-related traumas. Fifty patients, prior to the pandemic, when they were clinically stable, were treated with 15 mg/die vortioxetine, 44 with 450 mg/die trazodone, and 48 with 150 mg/die sertraline. After experiencing a major C
Who reads Differential Response to Three Antidepressants in Patients with Major Depressive Episode Who Suffered Covid-19-Related Trauma?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Ginevra Lombardozzi; Georgios D. Kotzalidis; Sergio De Filippis; Marta Matrone; Emanuela Amici; Giada Trovini; Filippo Perrini; Alessandro Di Giovanni; Valeria Giovanetti
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2022
- Language
- EN
- Field
- Neuroscience (Life Sciences)