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Can I read Predictive Factors for Severe Toxicity after Thoracic Chest Wall Reirradiation on EtoBox?
Predictive Factors for Severe Toxicity after Thoracic Chest Wall Reirradiation by S.K. Nguyen; D. Tremblay; A. Dagnault is a Medicine article available to read on EtoBox.
What is Predictive Factors for Severe Toxicity after Thoracic Chest Wall Reirradiation about?
MRSI at 3 T was performed to measure metabolic parameters, such as lac/pyre and ala/pyr ratios, in both kidneys. Animals were anesthetized (isoflurane and O 2 ) during the irradiation and imaging. Results: In our data at 15 Gy and both postirradiation times of 2-days and 21-days, 13 C spectra in kidneys clearly show pyr and its downstream metabolic products lac and ala. Further analyses indicate lac/pyr is lower in irradiated kidney than the nonirradiated kidney in comparison to a normal rat. Conclusions: Our data imply that metabolic response due to radiation-induced alterations in renal tissues can be detectable and quantifiable by this novel metabolic imaging technique. Application of hyperpolarized 13 C MRSI technique provides valuable tool to assess radiation-induced tissue damage.
Who reads Predictive Factors for Severe Toxicity after Thoracic Chest Wall Reirradiation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- S.K. Nguyen; D. Tremblay; A. Dagnault
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)