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Can I read Participant Engagement and Symptom Improvement: Aripiprazole Tablets with Sensor for the Treatment of Schizophrenia on EtoBox?
Participant Engagement and Symptom Improvement: Aripiprazole Tablets with Sensor for the Treatment of Schizophrenia by Jeffrey M Cochran; Hui Fang; Christophe Le Gallo; Timothy Peters-Strickland; Jean-Pierre Lindenmayer; J Corey Reuteman-Fowler is a Medicine article available to read on EtoBox.
What is Participant Engagement and Symptom Improvement: Aripiprazole Tablets with Sensor for the Treatment of Schizophrenia about?
## Purpose A recent, phase 3b, mirror-image clinical trial of outpatients with schizophrenia found that use of aripiprazole tablets with sensor (AS; Abilify MyCite^®^, comprising an ingestible event-marker sensor embedded in aripiprazole tablets, wearable sensor patches, and a smartphone application) reduced the incidence of psychiatric hospitalizations relative to oral standard-of-care antipsychotics. This analysis explored the relationship between AS engagement by participants and changes in participant performance and symptom-severity measures assessed by clinical raters. ## Participants and Methods This post hoc analysis used prospectively collected clinical data from a phase 3b clinical trial (NCT03892889). Outpatients had schizophrenia, were aged 18–65 years, and had ≥ 1 psychiatric hospitalization in the previous 48 months. Participants were grouped by study completion status and a k-means clustering algorithm based on AS utilization, resulting in 3 groups: discontinued (discontinued AS before month 3 of the study); moderate engagement (completed 3 months, used AS intermittently); and high engagement (completed 3 months, used AS regularly). Baseline to end-of-study differenc
Who reads Participant Engagement and Symptom Improvement: Aripiprazole Tablets with Sensor for the Treatment of Schizophrenia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jeffrey M Cochran; Hui Fang; Christophe Le Gallo; Timothy Peters-Strickland; Jean-Pierre Lindenmayer; J Corey Reuteman-Fowler
- Publisher
- Informa UK Limited
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)