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This document reports on the pharmacological properties of 14-cinnamoyloxycodeinone compared to morphine, highlighting its acute toxicity and analgesic potency in mice and rats. The study found that 14-cinnamoyloxycodeinone has a significantly lower LD50 value for intravenous administration and exhibits greater analgesic potency, with a faster onset and shorter duration of effect compared to morphine. Additionally, the compound shows a high capacity to produce physical dependence, as indicated by its

Author

Martin Johansson

Language

EN