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Morphodynamics of Ovarian Follicles During Oogenesis in Mice by Eimei Sato; Naoko Kimura; Masaki Yokoo; Yuko Miyake; Joh‐E Ikeda is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Morphodynamics of Ovarian Follicles During Oogenesis in Mice about?

## Abstract In the mouse, oogonia enter the prophase of the first meiotic division and differentiate into oocyte while developing in the fetal ovary. Shortly after birth, all oocytes are arrested in the dictyate stage of late prophase in the developing follicles; a small number of follicles reach the ovulatory stage; the rest are lost by apoptosis. The resumption of meiotic division and nuclear progression to metaphase II (oocyte maturation) occur in the ovulatory follicles. In this article we review recent morphological data that have clarified how cytokines and glycosaminoglycans (GAGs) are involved in mouse follicular development, atresia, and maturation during oogenesis, as exogenous/endogenous factors. (1) Microvascular networks and angiogenic factors (epidermal growth factor; GAGs) are deeply involved in selective mouse oocyte growth beyond ∼20–30 μm in diameter. (2) Gonadotropin‐inducible neuronal apoptosis inhibitory protein may indirectly affect oocyte survival as a result of the inhibition of apoptotic granulosa‐cell death during folliculogenesis. (3) The pattern of oocyte degeneration depends on follicle and oocyte developmental stages, and follicle stimulating hormone a

Who reads Morphodynamics of Ovarian Follicles During Oogenesis in Mice?

Author

Eimei Sato; Naoko Kimura; Masaki Yokoo; Yuko Miyake; Joh‐E Ikeda

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1059-910X)

Published

2006

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)