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Can I read Laser-induced fluorescence emission: I. The spectroscopic identification of fibrotic endocardium and myocardium on EtoBox?
Laser-induced fluorescence emission: I. The spectroscopic identification of fibrotic endocardium and myocardium by Masis Perk; Gregory J. Flynn; Carolyn Smith; Ben Bathgate; John Tulip; Wen Yue; Dr. Alexandra Lucas is a Medicine article available to read on EtoBox.
What is Laser-induced fluorescence emission: I. The spectroscopic identification of fibrotic endocardium and myocardium about?
Laser-induced fluorescence has been developed as a guidance system for laser angioplasty. Laser ablation has been used for resection of arrhythmogenic ventricular scar. We have investigated the use of laser-induced fluorescence for the detection of fibrotic and ischemic changes in endocardium and myocardium. Fluorescence emission spectra from human necropsy specimens were correlated with histologic examination. Normalized fluorescence intensity detected from both the endocardia1 and the myocardial surfaces of the fibrotic ventricular specimens was significantly higher than that of corresponding normal specimens at 440 to 475 nm. Fibrotic endocardium could be identified by a fluorescence emission intensity ratio less than 1.5 for wavelength ratio 375/450nm. Acutely infarcted endocardium was recognizable by a ratio of 1.5 to 2.0. The specificity and sensitivity of detection of scarred endocardium was 70 and loo%, respectively. Fibrotic myocardium was also consistently identified by fluorescence spectroscopy. Conclusion: Fluorescence emission spectroscopy can differentiate normal and fibrotic endocardium and myocardium, in vitro. This technique may be useful for guidance during laser
Who reads Laser-induced fluorescence emission: I. The spectroscopic identification of fibrotic endocardium and myocardium?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Masis Perk; Gregory J. Flynn; Carolyn Smith; Ben Bathgate; John Tulip; Wen Yue; Dr. Alexandra Lucas
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)
- Published
- 1990
- Language
- EN
- Field
- Medicine (Health Sciences)