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Cognitive Deficit And Cardiovascular Risk In Community-dwelling Elderly by Monteiro Bezerra, M.M. ;Borges, S.M. ;Vivas, I. ;Rosa, J. ;Uchida, J.E. is a Social Sciences article available to read on EtoBox.

What is Cognitive Deficit And Cardiovascular Risk In Community-dwelling Elderly about?

Decreased cerebral perfusion due to reduced arterial compliance is linked to cognitive and physical impairment in aging adults with overt vascular disease. However, this association, as well as its racial (black-white) disparities, have not been thoroughly elucidated in non-institutionalized middle-aged adults. Our analyses considered 471 participants of the Bogalusa Heart Study (mean age 48.2 years, 33.8% blacks, 58.6% females) with available information on arterial compliance -assessed non-invasively via aorto-femoral pulse wave velocity (afPWV)-in two time points (mean follow-up 12.7 years), as well as cognitive and physical function assessed later in life. Black participants with impaired physical and cognitive function showed significantly greater yearly progression of afPWV compared to white participants. In multivariable-adjusted logistic regression analyses, yearly progression of afPWV was significantly associated with decreased cognitive and physical function, in black participants only. These findings suggest a race-specific differential impact of decreasing vascular compliance over time on impaired cognitive/physical function in middle-aged adults. More multidisciplinary

Who reads Cognitive Deficit And Cardiovascular Risk In Community-dwelling Elderly?

Author

Monteiro Bezerra, M.M. ;Borges, S.M. ;Vivas, I. ;Rosa, J. ;Uchida, J.E.

Publisher

Oxford University Press; Oxford: Oxford University Press; Oxford University Press (OUP) (ISSN 2399-5300)

Published

2017

Language

EN

Field

Social Sciences