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Clinical Covariates of Abnormal Heart Rate Turbulence in Coronary Patients by Iwona Cygankiewicz; Jerzy Krzysztof Wranicz; Janusz Zaslonka; Halina Bolinska; Wojciech Zareba is a Medicine article available to read on EtoBox.

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**Background:** The aim of this study is to evaluate the association between heart rate turbulence (HRT) parameters and clinical characteristics of coronary artery disease (CAD) patients. **Methods and Results:** In 122 patients (mean age 62 ± 9 years) with angiographically documented CAD, 24‐hour Holter monitoring with HRT analysis was performed to evaluate turbulence onset (TO) and turbulence slope (TS). There was a significant correlation between TO and TS (P =−0.31; P < 0.001). According to quartile values, TO ≥−0.37% and TS ≤ 4.25 ms/RR were considered as abnormal in this patient population. Average values of TO were higher and TS lower in patients over 60 years, in patients with a past history of myocardial infarction and in those with EF < 40%. Considering pharmacotheraphy, higher (better) values of TS were observed in patients on statins, nitrates, and beta‐blockers while lower TS values were noted in patients on calcium blockers. Patients with abnormal parameters of HRT compared to group with normal HRT values were characterized by features of more advanced CAD: age over 60 years (75% vs 49%), past history of MI (75% vs 64%), and EF 60 years (OR 1.27; P = 0.002) and EF <

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Author

Iwona Cygankiewicz; Jerzy Krzysztof Wranicz; Janusz Zaslonka; Halina Bolinska; Wojciech Zareba

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1542-474X)

Published

2003

Language

EN

Field

Medicine (Health Sciences)