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Can I read An MRI protocol for anatomical and functional evaluation of the California sea lion brain on EtoBox?
An MRI protocol for anatomical and functional evaluation of the California sea lion brain by Peter F. Cook; Vanessa A. Hoard; Sudipto Dolui; Blaise deB Frederick; Richard Redfern; Sophie E. Dennison; Barbie Halaska; Josh Bloom; Kris T. Kruse-Elliott; Emily R. Whitmer; Emily J. Trumbull; Gregory S. Berns; John A. Detre; Mark D’Esposito; Frances M.D. Gulland; Colleen Reichmuth; Shawn P. Johnson; Cara L. Field; Ben A. Inglis is a Neuroscience article available to read on EtoBox.
What is An MRI protocol for anatomical and functional evaluation of the California sea lion brain about?
## Background: Domoic acid (dom) is a neurotoxin produced by some harmful algae blooms in coastal waters. california sea lions (zalophus californianus) exposed to dom often strand on beaches where they exhibit a variety of symptoms, including seizures. these animals typically show hippocampal atrophy on mri scans. ## New method: We describe an mri protocol for comprehensive evaluation of dom toxicosis in the sea lion brain. we intend to study brain development in pups exposed in utero. the protocol depicts the hippocampal formation as the primary region of interest. we include scans for quantitative morphometry, functional and structural connectivity, and a cerebral blood flow map. ## Results: High-resolution 3d anatomical scans facilitate post hoc slicing in arbitrary planes and accurate morphometry. we demonstrate the first cerebral blood flow map using mri, and the first structural tractography from a live sea lion brain. ## Comparison with existing methods: Scans were compared to prior anatomical and functional studies in live sea lions, and structural connectivity in post mortem specimens. hippocampal volumes were broadly in line with prior studies, with differences likely att
Who reads An MRI protocol for anatomical and functional evaluation of the California sea lion brain?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Peter F. Cook; Vanessa A. Hoard; Sudipto Dolui; Blaise deB Frederick; Richard Redfern; Sophie E. Dennison; Barbie Halaska; Josh Bloom; Kris T. Kruse-Elliott; Emily R. Whitmer; Emily J. Trumbull; Gregory S. Berns; John A. Detre; Mark D’Esposito; Frances M.D. Gulland; Colleen Reichmuth; Shawn P. Johnson; Cara L. Field; Ben A. Inglis
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Neuroscience (Life Sciences)