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01) Administration of Vorinostat Disrupts HIV-1 Latency by July Santos is a document available to read on EtoBox.
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Proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to curing the infection. Inducing the expression of latent genomes within resting CD41 T cells is the primary strategy to clear this reservoir. In each of eight patients, a single dose of VOR increased both biomarkers of cellular acetylation and simultaneously induced an increase in HIV RNA expression.
- Author
- July Santos
- Language
- EN