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Hypermethylation of The BRCA2 Gene Promoter and It by Bright Onkemetse is a document available to read on EtoBox.
The study investigates the hypermethylation of the BRCA2 gene promoter and its co-hypermethylation with the BRCA1 gene promoter in breast cancer patients. Results indicate that hypermethylation of BRCA2 is significantly more frequent in tumor tissues of breast cancer patients compared to controls, particularly in those over 50 years old and with higher Ki67 expression levels. The findings support the role of BRCA2 hypermethylation in breast cancer pathogenesis and highlight the importance of assessing its r
- Author
- Bright Onkemetse
- Language
- EN