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Challenges in the Diagnosis of Tuberculous Meningitis by Foppiano Palacios, Carlo; Saleeb, Paul G is a Medicine article available to read on EtoBox.

What is Challenges in the Diagnosis of Tuberculous Meningitis about?

Tuberculosis (TB) continues to pose a significant public health problem. Tuberculous meningitis (TBM) is the most severe form of extra-pulmonary TB. TBM carries a high mortality rate, including for those receiving treatment for TB. Diagnosis of TBM is difficult for clinicians as it can clinically present similarly to other forms of meningitis. The difficulty in diagnosis often leads to a delay in treatment and subsequent mortality. Those who survive are left with long-term sequelae leading to lifelong disability. The microbiologic diagnosis of TBM requires the isolation of Mycobacterium tuberculosis from the cerebrospinal fluid (CSF) of an infected patient. The diagnosis of tuberculous meningitis continues to be challenging for clinicians. Unfortunately, many cases of TBM cannot be confirmed based on clinical and imaging findings as the clinical findings are nonspecific, while laboratory techniques are largely insensitive or slow. Until recently, the lack of accessible and timely tests has contributed to a delay in diagnosis and subsequent morbidity and mortality for many patients, particularly those in resourcelimited settings. The availability of Xpert Ultra and point-of-care lip

Who reads Challenges in the Diagnosis of Tuberculous Meningitis?

Author

Foppiano Palacios, Carlo; Saleeb, Paul G

Publisher

Elsevier ; Elsevier Limited; London: Elsevier Ltd.; Elsevier BV (ISSN 2405-5794)

Published

2020

Language

EN

Field

Medicine (Health Sciences)