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Fate of Pulmonary Nodules Detected by Computer-aided Diagnosis and Physician Review on the Computed Tomography Simulation Images for Hepatocellular Carcinoma by Hyojung Park; Jin-Sung Kim; Hee Chul Park; Dongryul Oh is a Medicine article available to read on EtoBox.

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## Purpose To investigate the frequency and clinical significance of detected incidental lung nodules found on computed tomography (CT) simulation images for hepatocellular carcinoma (HCC) using computer-aided diagnosis (CAD) and a physician review. ## Materials and Methods Sixty-seven treatment-naïve HCC patients treated with transcatheter arterial chemoembolization and radiotherapy (RT) were included for the study. Portal phase of simulation CT images was used for CAD analysis and a physician review for lung nodule detection. For automated nodule detection, a commercially available CAD system was used. To assess the performance of lung nodule detection for lung metastasis, the sensitivity, negative predictive value (NPV), and positive predictive value (PPV) were calculated. ## Results Forty-six patients had incidental nodules detected by CAD with a total of 109 nodules. Only 20 (18.3%) nodules were considered to be significant nodules by a physician review. The number of significant nodules detected by both of CAD or a physician review was 24 in 9 patients. Lung metastases developed in 11 of 46 patients who had any type of nodule. The sensitivities were 58.3% and 100% based on pa

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Author

Hyojung Park; Jin-Sung Kim; Hee Chul Park; Dongryul Oh

Publisher

Korean Society for Therapeutic Radiology and Oncology

Published

2014

Language

EN

Field

Medicine (Health Sciences)