Opening book details…
Can I read Construction of Polyfunctionalized 6–5–5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction on EtoBox?
Construction of Polyfunctionalized 6–5–5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction by Zhu, Fu-Ping; Guo, Xiang; Zhang, Fu-Min; Zhang, Xiao-Ming; Wang, Hong; Tu, Yong-Qiang is a Chemistry article available to read on EtoBox.
What is Construction of Polyfunctionalized 6–5–5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction about?
A novel one-pot semipinacol rearrangement/Michael addition/Henry reaction of vinylogous α-ketols with nitroolefins has been achieved through the promotion of two Lewis acids, namely, TMSOTf and TiCl, at temperatures between 0 and -78 °C. A range of synthetically challenging polyfunctionalized 6-5-5 and 7-5-5 fused tricyclic carbocycles bearing up to five continuous stereocenters, including one quaternary carbon center, are rapidly constructed in moderate to good yields with good to high diastereoselectivities in most cases.
Who reads Construction of Polyfunctionalized 6–5–5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Zhu, Fu-Ping; Guo, Xiang; Zhang, Fu-Min; Zhang, Xiao-Ming; Wang, Hong; Tu, Yong-Qiang
- Publisher
- American Chemical Society; American Chemical Society (ACS); Test accounts (ISSN 1523-7060)
- Published
- 2020
- Language
- EN
- Field
- Chemistry (Physical Sciences)