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Can I read Resveratrol Accelerates Wound Healing by Attenuating Oxidative Stress-induced Impairment of Cell Proliferation and Migration on EtoBox?
Resveratrol Accelerates Wound Healing by Attenuating Oxidative Stress-induced Impairment of Cell Proliferation and Migration by Zhou, Xueqing; Ruan, Qiongfang; Ye, Ziqing; Chu, Zhigang; Xi, Maomao; Li, Min; Hu, Weigang; Guo, Xiaoyu; Yao, Paul; Xie, Weiguo is a Medicine article available to read on EtoBox.
What is Resveratrol Accelerates Wound Healing by Attenuating Oxidative Stress-induced Impairment of Cell Proliferation and Migration about?
Background: Impaired wound healing, which is due to various external and internal factors that are involved in wound pathophysi Q5 ology, leads to high rates of morbidity and mortality worldwide. Oxidative stress injury is an important factor that affects wound healing by changing the whole healing process. So, resveratrol, a dietary fruits polyphenol, which is known for its antioxidant properties, maybe the candidate to accelerate the wound-healing process. ## Methods: The Human Umbilical Vein Endothelial Cells (HUVECs) was used for in vitro experiments to evaluate the effect of resveratrol on hyperglycemia-induced gene expression, oxidative stress and cell proliferation. The diabetic rat model was used to evaluate the effect of resveratrol on cutaneous burn injury healing process. ## Results : Increases in H 2 O 2 decreased cell viability with the 0À800 mM concentration range, and resveratrol could protect HUVECs against H 2 O 2 -induced injury. The scratched wound closed rate in H 2 O 2 group was significantly smaller than the Control group (p < 0.05) and Resveratrol + H 2 O 2 group (p < 0.05). The fluorescence intensity of ROS was lower in Control and Resveratrol + H 2 O 2 grou
Who reads Resveratrol Accelerates Wound Healing by Attenuating Oxidative Stress-induced Impairment of Cell Proliferation and Migration?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Zhou, Xueqing; Ruan, Qiongfang; Ye, Ziqing; Chu, Zhigang; Xi, Maomao; Li, Min; Hu, Weigang; Guo, Xiaoyu; Yao, Paul; Xie, Weiguo
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0305-4179)
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)