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Classical anti-psychotic, anti-calmodulin drugs were noted here to inhibit Ca2+-uptake via the vanilloid inducible Ca2+ channel / inflamatory pain receptor 1 (TRPV1) Functional assays on TRPV1 expressing cells support direct, dose-dependent inhibition of vanilloid-induced 45Ca2+uptake at mM concentrations: calmidazolium (broad range)$trifluoperazine (narrow range).chlorpromaz

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