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Can I read Label free CMOS DNA image sensor based on the charge transfer technique on EtoBox?
Label free CMOS DNA image sensor based on the charge transfer technique by Y. Maruyama; S. Terao; K. Sawada is a Engineering article available to read on EtoBox.
What is Label free CMOS DNA image sensor based on the charge transfer technique about?
This paper describes a label free and fully electronic 32x32 CMOS DNA image sensor fabricated in a 1-poly 1-metal CMOS technology, suitable for inexpensive and highly integrated applications. The pixel operates using the charge transfer technique. DNA immobilization and hybridization on the silane-coated surface are detected, as well as variations in the silane coating. Significant output voltages of 76.4+/-16.5 mV and 64.5+/-15.7 mV were measured after immobilization and hybridization of DNA molecules containing 22 bases. From these results, the immobilized and hybridized DNA densities were estimated. These were 6.3+/-1.4x10(8) cm(-2) and 5.3+/-1.3x10(8) cm(-2), respectively. The DNA detection limit was calculated to be approximately 2.7x10(7) cm(-2) molecules (22 bases). Thanks to its potentiometric detectability, the DNA immobilization and hybridization was successfully verified.
Who reads Label free CMOS DNA image sensor based on the charge transfer technique?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- Y. Maruyama; S. Terao; K. Sawada
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0956-5663)
- Published
- 2009
- Language
- EN
- Field
- Engineering (Physical Sciences)