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What is Retronecine: Toxicity and Uses about?

Retronecine is a pyrrolizidine alkaloid found in plants like Senecio and Crotalaria that is toxic, especially to the liver. It is composed of necine bases and acids that give it structural diversity. Retronecine can be used by organisms like Utetheisa ornatrix caterpillars as a defense against predators, though ingestion by humans and animals leads to conditions like veno-occlusive disease and liver toxicity. Long term effects can include liver tumors and cancer due to DNA damage caused by retronecine and i

Author

Yen Bum

Language

EN