Can I read Non-melanoma skin cancer may be a marker of poor prognosis in patients with non-Hodgkin's lymphoma on EtoBox?

Non-melanoma skin cancer may be a marker of poor prognosis in patients with non-Hodgkin's lymphoma by Henrik Hjalgrim; Morten Frisch; Hans H. Storm; Bengt Glimelius; Jakob Bøje Pedersen; Mads Melbye is a Medicine article available to read on EtoBox.

What is Non-melanoma skin cancer may be a marker of poor prognosis in patients with non-Hodgkin's lymphoma about?

According to recent results, patients with non-melanoma skin cancers are at increased risk of developing non-Hodgkin's lymphoma (NHL). The prognostic significance of this association is unknown. Two cohorts of patients with a first diagnosis of non-melanoma skin cancer and a subsequent diagnosis of either NHL (n = 170) or colon cancer (n = 435) were established using national cancer registry data in Denmark. Two other cohorts of patients in whom NHL (n = 600) or colon cancer (n = 1,541) was the patients' first known malignancy served as comparison groups. Mortality rates were compared using Cox's regression analysis. Among patients younger than 80 years at NHL diagnosis, a history of non-melanoma skin cancer was associated with significantly increased mortality [relative risk (RR) = 1.54; 95% confidence interval: 1.19-1.99]. This association was present in both men (RR = 1.38; 1.02-1.86) and women (RR = 2.15; 1.31-3.54) and was similar after both major subtypes of non-melanoma skin cancer. Overall, antedating non-melanoma skin cancer had no prognostic significance for colon cancer patients (RR = 1.00; 0.84-1.18). Whatever the underlying mechanism, our observation has potential clin

Who reads Non-melanoma skin cancer may be a marker of poor prognosis in patients with non-Hodgkin's lymphoma?

Author

Henrik Hjalgrim; Morten Frisch; Hans H. Storm; Bengt Glimelius; Jakob Bøje Pedersen; Mads Melbye

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

2000

Language

EN

Field

Medicine (Health Sciences)