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Can I read Mechanistic Insights Into Consumption of the Food Additive Xanthan Gum by the Human Gut Microbiota on EtoBox?
Mechanistic Insights Into Consumption of the Food Additive Xanthan Gum by the Human Gut Microbiota by Matthew P. Ostrowski; Sabina Leanti La Rosa; Benoit J. Kunath; Andrew Robertson; Gabriel Pereira; Live H. Hagen; Neha J. Varghese; Ling Qiu; Tianming Yao; Gabrielle Flint; James Li; Sean P. McDonald; Duna Buttner; Nicholas A. Pudlo; Matthew K. Schnizlein; Vincent B. Young; Harry Brumer; Thomas M. Schmidt; Nicolas Terrapon; Vincent Lombard; Bernard Henrissat; Bruce Hamaker; Emiley A. Eloe-Fadrosh; Ashootosh Tripathi; Phillip B. Pope; Eric C. Martens is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Mechanistic Insights Into Consumption of the Food Additive Xanthan Gum by the Human Gut Microbiota about?
Processed foods often include food additives such as xanthan gum, a complex polysaccharide with unique rheological properties, that has established widespread use as a stabilizer and thickening agent. Xanthan gum's chemical structure is distinct from those of host and dietary polysaccharides that are more commonly expected to transit the gastrointestinal tract, and little is known about its direct interaction with the gut microbiota, which plays a central role in digestion of other dietary fibre polysaccharides. Here we show that the ability to digest xanthan gum is common in human gut microbiomes from industrialized countries and appears contingent on a single uncultured bacterium in the family Ruminococcaceae. Our data reveal that this primary degrader cleaves the xanthan gum backbone before processing the released oligosaccharides using additional enzymes. Some individuals harbour Bacteroides intestinalis that is incapable of consuming polymeric xanthan gum but grows on oligosaccharide products generated by the Ruminococcaceae. Feeding xanthan gum to germfree mice colonized with a human microbiota containing the uncultured Ruminococcaceae supports the idea that the additive xant
Who reads Mechanistic Insights Into Consumption of the Food Additive Xanthan Gum by the Human Gut Microbiota?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Matthew P. Ostrowski; Sabina Leanti La Rosa; Benoit J. Kunath; Andrew Robertson; Gabriel Pereira; Live H. Hagen; Neha J. Varghese; Ling Qiu; Tianming Yao; Gabrielle Flint; James Li; Sean P. McDonald; Duna Buttner; Nicholas A. Pudlo; Matthew K. Schnizlein; Vincent B. Young; Harry Brumer; Thomas M. Schmidt; Nicolas Terrapon; Vincent Lombard; Bernard Henrissat; Bruce Hamaker; Emiley A. Eloe-Fadrosh; Ashootosh Tripathi; Phillip B. Pope; Eric C. Martens
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)