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Admission eGFR predicts in-hospital mortality independently of admission glycemia and C-peptide in patients with type 2 diabetes mellitus and COVID-19 by Marco Infante; Massimo Pieri; Santina Lupisella; Ali Mohamad; Sergio Bernardini; David Della-Morte; Andrea Fabbri; Alberto De Stefano; Marco Iannetta; Lorenzo Ansaldo; Angela Crea; Massimo Andreoni; Maria Morello is a Medicine article available to read on EtoBox.
What is Admission eGFR predicts in-hospital mortality independently of admission glycemia and C-peptide in patients with type 2 diabetes mellitus and COVID-19 about?
Abstract Objective Type 2 diabetes mellitus (T2DM) and impaired kidney function are associated with a higher risk of poor outcomes of coronavirus disease 2019 (COVID-19). We conducted a retrospective study in hospitalized T2DM patients with COVID-19 to assess the association between in-hospital mortality and admission values of different hematological/biochemical parameters, including estimated glomerular filtration rate (eGFR), plasma glucose and C-peptide (the latter serving as a marker of beta-cell function). Methods The study included T2DM patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who were consecutively admitted to our Institution between 1 October 2020 and 1 April 2021. Results Patients ( n = 74) were categorized into survivors ( n = 55) and non-survivors ( n = 19). Non-survivors exhibited significantly higher median white blood cell (WBC) count, D-dimer, neutrophil-to-lymphocyte ratio, high-sensitivity C-reactive protein (hsCRP), and procalcitonin levels, as well as significantly lower median serum 25-hydroxyvitamin D [25(OH)D] levels compared to survivors. Non-survivors exhibited significantly higher median admission plasm
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- Author
- Marco Infante; Massimo Pieri; Santina Lupisella; Ali Mohamad; Sergio Bernardini; David Della-Morte; Andrea Fabbri; Alberto De Stefano; Marco Iannetta; Lorenzo Ansaldo; Angela Crea; Massimo Andreoni; Maria Morello
- Publisher
- Informa UK Limited
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)