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New Trends in Personalized Treatment of Depression by Gaia Sampogna; Claudia Toni; Pierluigi Catapano; Bianca Della Rocca; Matteo Di Vincenzo; Mario Luciano; Andrea Fiorillo is a Psychology article available to read on EtoBox.

What is New Trends in Personalized Treatment of Depression about?

## Purpose of review Major depressive disorder (MDD) is a common and burdensome severe mental disorder, which is expected to become the leading cause of disease burden worldwide. Most patients with MDD remain untreated/undertreated. For many decades “a trial and error” approach has been adopted for selecting the best treatment plan for each individual patient, but more recently a personalized treatment approach has been proposed, by taking into account several individual and clinical factors (e.g., clinical stage, comorbidity, duration of illness). Therefore, the aim of this study is to address the most relevant innovations in the personalized treatment plan for patients with MDD. ## Recent findings In recent years, several pharmacological and nonpharmacological innovations have been introduced in the treatment of patients with MDD. As regards pharmacological treatments, the newly developed drugs have an innovative mechanism of action, targeting the glutamatergic systems. These drugs are highly effective in improving depressive symptoms, with a good level of safety and tolerability. As regards nonpharmacological interventions, innovations include both new strategies targeting diffe

Who reads New Trends in Personalized Treatment of Depression?

Author

Gaia Sampogna; Claudia Toni; Pierluigi Catapano; Bianca Della Rocca; Matteo Di Vincenzo; Mario Luciano; Andrea Fiorillo

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2023

Field

Psychology (Social Sciences)