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An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays by Orooji, Yasin; Sohrabi, Hessamaddin; Hemmat, Nima; Oroojalian, Fatemeh; Baradaran, Behzad; Mokhtarzadeh, Ahad; Mohaghegh, Mohamad; Karimi-Maleh, Hassan is a Engineering article available to read on EtoBox.

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## Abstract A novel coronavirus of zoonotic origin (SARS-CoV-2) has recently been recognized in patients with acute respiratory disease. COVID-19 causative agent is structurally and genetically similar to SARS and bat SARS-like coronaviruses. The drastic increase in the number of coronavirus and its genome sequence have given us an unprecedented opportunity to perform bioinformatics and genomics analysis on this class of viruses. Clinical tests like PCR and ELISA for rapid detection of this virus are urgently needed for early identification of infected patients. However, these techniques are expensive and not readily available for point-of-care (POC) applications. Currently, lack of any rapid, available, and reliable POC detection method gives rise to the progression of COVID-19 as a horrible global problem. To solve the negative features of clinical investigation, we provide a brief introduction of the general features of coronaviruses and describe various amplification assays, sensing, biosensing, immunosensing, and aptasensing for the determination of various groups of coronaviruses applied as a template for the detection of SARS-CoV-2. All sensing and biosensing techniques deve

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Author

Orooji, Yasin; Sohrabi, Hessamaddin; Hemmat, Nima; Oroojalian, Fatemeh; Baradaran, Behzad; Mokhtarzadeh, Ahad; Mohaghegh, Mohamad; Karimi-Maleh, Hassan

Publisher

Nano-Micro Letters; Springer-Verlag; Open Access Science Online; Fayetteville Ark.: OAHOST; Springer Science and Business Media LLC; Springer Nature (ISSN 2311-6706)

Published

2020

Language

EN

Field

Engineering (Physical Sciences)