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Effect of different glucose concentrations on proteome of Saccharomyces cerevisiae by Guidi Francesca; Magherini Francesca; Gamberi Tania; Borro Marina; Simmaco Maurizio; Modesti Alessandra is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Effect of different glucose concentrations on proteome of Saccharomyces cerevisiae about?
We performed a proteomic study to understand how Saccharomyces cerevisiae adapts its metabolism during the exponential growth on three different concentrations of glucose; this information will be necessary to understand yeast carbon metabolism in different environments. We induced a natural diauxic shift by growing yeast cells in glucose restriction thus having a fast and complete glucose exhaustion. We noticed differential expressions of groups of proteins. Cells in high glucose have a decreased growth rate during the initial phase of fermentation; in glucose restriction and in high glucose we found an over-expression of a protein (Peroxiredoxin) involved in protection against oxidative stress insult. The information obtained in our study validates the application of a proteomic approach for the identification of the molecular bases of environmental variations such as fermentation in high glucose and during a naturally induced diauxic shift.
Who reads Effect of different glucose concentrations on proteome of Saccharomyces cerevisiae?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Guidi Francesca; Magherini Francesca; Gamberi Tania; Borro Marina; Simmaco Maurizio; Modesti Alessandra
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1570-9639)
- Published
- 2010
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)