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The article presents a novel microneedle patch technology that utilizes catechol-based chemistry for the glucose-responsive delivery of zinc-glucagon (Z-GCN) to prevent hypoglycemia in insulin-dependent diabetes patients. The patch is designed to release Z-GCN when glucose levels drop, using a mechanism that involves competitive binding between catechol and boronic acid groups in response to glucose concentration changes. In vivo studies demonstrate the patch

Author

mkg bb

Language

EN