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Can I read A Review of Paroxysmal Sympathetic Hyperactivity After Acquired Brain Injury on EtoBox?

A Review of Paroxysmal Sympathetic Hyperactivity After Acquired Brain Injury by Iain Perkes; Ian J. Baguley; Melissa T. Nott; David K. Menon is a Medicine article available to read on EtoBox.

What is A Review of Paroxysmal Sympathetic Hyperactivity After Acquired Brain Injury about?

## Abstract Severe excessive autonomic overactivity occurs in a subgroup of people surviving acquired brain injury, the majority of whom show paroxysmal sympathetic and motor overactivity. Delayed recognition of paroxysmal sympathetic hyperactivity (PSH) after brain injury may increase morbidity and long‐term disability. Despite its significant clinical impact, the scientific literature on this syndrome is confusing; there is no consensus on nomenclature, etiological information for diagnoses preceding the condition is poorly understood, and the evidence base underpinning our knowledge of the pathophysiology and management strategies is largely anecdotal. This systematic literature review identified 2 separate categories of paroxysmal autonomic overactivity, 1 characterized by relatively pure sympathetic overactivity and another group of disorders with mixed parasympathetic/sympathetic features. The PSH group comprised 349 reported cases, with 79.4% resulting from traumatic brain injury (TBI), 9.7% from hypoxia, and 5.4% from cerebrovascular accident. Although TBI is the dominant causative etiology, there was some suggestion that the true incidence of the condition is highest follo

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It is typically read by researchers, students, and practitioners in Medicine.

Author
Iain Perkes; Ian J. Baguley; Melissa T. Nott; David K. Menon
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0364-5134)
Published
2010
Language
EN
Field
Medicine (Health Sciences)

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