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Redefining the association of triglycerides with all-cause and Cardiovascular Disease Mortality in the Chinese population: a nationwide, population-based, prospective cohort study of 3.8 million Chinese adults by Guangyu Li & Linkang He & Xueke Bai & Shi Chen & Hao Dai & Guangda He & Yang Yang & Xiaoyan Zhang & Jianlan Cui & Xi Li & Chris Packard & Jan Boren & Liang Chen & Shengshou Hu is a book available to read on EtoBox.

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The Lancet Regional Health - Western Pacific, 63 (2025) 101689. doi:10.1016/j.lanwpc.2025.101689SummaryThe Lancet RegionalHealth - WesternBackground Current international guidelines on dyslipidemia were formulated based on the research performedPacific 2025;63:mostly in White populations. However, whether the association of triglycerides (TGs) with cardiovascular disease101689(CVD) differs between Chinese and White populations is unknown.Published Online xxxMethods 3,789,025 participants from the China Health Evaluation And risk Reduction through nationwide Team (ChinaHEART) were evaluated for the association between TGs and all-cause and CVD mortality with Cox101689regression models. The findings were tested for sex-specific differences and contrasted with another comparisoncohort of 434,919 UK Biobank participants.Findings 92,888 Chinese adults died during a median follow-up of 4.6 years. All-cause and CVD mortality initiallyincreased with TG elevation abruptly and plateaued in Chinese men, while U-shaped associations were seen inChinese women. In contrast, CVD risk increased incrementally with TGs in White people. Hazard ratios (95%confidence intervals) were 1.02 (0.97–1.07), 1

Author
Guangyu Li & Linkang He & Xueke Bai & Shi Chen & Hao Dai & Guangda He & Yang Yang & Xiaoyan Zhang & Jianlan Cui & Xi Li & Chris Packard & Jan Boren & Liang Chen & Shengshou Hu
Publisher
The Author(s)
Published
2025
Language
EN

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