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There is a need for physiologically relevant in vitro models that recreate mechanical loading conditions seen in normal and pathological heart conditions. To address this need, researchers developed a microfluidic cardiac cell culture model (μCCCM) that allows cardiomyocytes to be mechanically stimulated in vitro by directly coupling cell structure and function to fluid-induced loading. In this model, cells are cultured on a flexible silicone membrane in a small chamber. Integrating the chamber with a pump,

Author

ginnaparra19

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EN