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Signal Transduction and Cardiac Hypertrophy by Florian Grabellus, Bodo Levkau, Hans-H. Scheld, Atsushi Takeda, Michael Erren (auth.), Naranjan S. Dhalla PhD, MD (Hon), DSc (Hon), Larry V. Hryshko PhD, Elissavet Kardami PhD, Pawan K. Singal PhD, DSc (eds.) is a nonfiction available to read on EtoBox.

What is Signal Transduction and Cardiac Hypertrophy about?

Cellular signaling in cardiac muscle refers to the myriad of stimuli and responses that direct and control the physiological operation of this organ. Our understand­ ing of these complex signaling cascades has increased dramatically over the past few decades with the advent of molecular tools for their dissection. Moreover, this infor­ mation is beginning to provide tangible targets towards manipulating cardiac func­ tion in the setting of cardiovascular disease. The mechanisms and factors that regulate cardiac cell growth are of particular interest as both adaptive and maladaptive responses can occur during cardiac hypertrophy. Cardiac hypertrophy describes the increase in individual cardiac myocyte size that is accomplished through the series and/or parallel addition of sarcomeres. The ability of cardiac muscle to increase in size through hyperplasia becomes highly restricted or negligible shortly after birth. Consequently, the increase in heart size associated with development and growth of an individual occurs through hypertrophy. In response to a chronic increase in workload, cardiac muscle cells can dramatically increase in size to face their increasing contractile demands. W

Who reads Signal Transduction and Cardiac Hypertrophy?

Author

Florian Grabellus, Bodo Levkau, Hans-H. Scheld, Atsushi Takeda, Michael Erren (auth.), Naranjan S. Dhalla PhD, MD (Hon), DSc (Hon), Larry V. Hryshko PhD, Elissavet Kardami PhD, Pawan K. Singal PhD, DSc (eds.)

Publisher

Springer US Imprint: Springer

Published

2003

Language

EN

ISBN

9781402071959

Category

nonfiction

Subjects

Medical, Science, Chemistry