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Hereditary Diabetes Insipidus: an Immunohistochemical Study of the Hypothalamus and Pituitary Gland by C. Bergeron; K. Kovacs; C. Ezrin; C. Mizzen is a Medicine article available to read on EtoBox.

What is Hereditary Diabetes Insipidus: an Immunohistochemical Study of the Hypothalamus and Pituitary Gland about?

We report the histological findings in a case of hereditary diabetes insipidus (HDI) using vasopressin (VP) immunohistochemistry. The hypothalamus displayed a marked loss of magnocellular VP neurons, with preservation of the smaller cells. The neurohypophysis was severely atrophic with scanty immunoreactivity. Our results support the hypothesis that HDI results from a selective degeneration of VP neurons affecting chiefly the magnocellular elements projecting to the neurohypophysis. The sparing of the parvocellular component may reflect the projection of these neurons to non-pituitary targets.

Who reads Hereditary Diabetes Insipidus: an Immunohistochemical Study of the Hypothalamus and Pituitary Gland?

Author

C. Bergeron; K. Kovacs; C. Ezrin; C. Mizzen

Publisher

Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0001-6322)

Published

1990

Language

EN

Field

Medicine (Life Sciences)