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Can I read Role of Autoantibody Testing on EtoBox?
Role of Autoantibody Testing by Amita Aggarwal is a Medicine article available to read on EtoBox.
What is Role of Autoantibody Testing about?
Autoantibodies are the serological hallmark of autoimmune disease. Though their pathogenic role is debatable, they play an important role in the management of a patient with rheumatic disease. However, due to their presence in the general population as well as in multiple autoimmune diseases, the presence of an autoantibody alone does not make a diagnosis; the result has to be interpreted along with clinical findings. Similarly, the absence of autoantibody does not exclude a disease. The common autoantibodies used in clinical practice include rheumatoid factor, anti-CCP antibodies, antinuclear antibodies (ANAs), anti-neutrophil cytoplasmic antibodies (ANCA) and antiphospholipid antibodies. Once an autoantibody to a broad antigen is detected in a patient, sub-specificity analysis can improve the utility of the antibody. Autoantibodies are detected in the serum using different assays and results of which can vary; thus, it is important for a clinician to know the method used, its sensitivity and specificity to help in the proper interpretation of the laboratory results. This review will address these issues.
Who reads Role of Autoantibody Testing?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Amita Aggarwal
- Publisher
- Elsevier BV
- Published
- 2014
- Language
- EN
- Field
- Medicine (Health Sciences)