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Short- and long-term outcomes after Kasai operation for type III biliary atresia: Twenty years of experience in a single tertiary Egyptian center-A retrospective cohort study by Emad Hamdy Gad; Yasmin Kamel; Tahany Abdel-Hameed Salem; Mohammed Abdel-Hafez Ali; Ahmed Nabil Sallam is a Medicine article available to read on EtoBox.
What is Short- and long-term outcomes after Kasai operation for type III biliary atresia: Twenty years of experience in a single tertiary Egyptian center-A retrospective cohort study about?
## Objectives Kasai portoenterostomy(KPE) is the treatment of choice for the fatal devastating infantile type III biliary atresia (BA). The study aimed to analyze short-and long-term outcomes after this procedure and their predictors in a tertiary center. Methods: We retrospectively analyzed 410 infants who underwent KPE for type III BA in the period from February 2000 to December 2019. The overall male/female ratio was 186/224. Results: The early (>6months) complications involved 187(45.6%) of our infants with a higher incidence of early cholangitis that affected 108(26.3%) of them. The jaundice clearance at the 6th post-operative month that reached 138(33.7%) of them had an independent correlation with mild portal tracts ductal and/or ductular proliferation, using postoperative steroids therapy, and absence of early postoperative cholangitis. The early infant mortality that affected 70(17.1%) of our patients was mostly from sepsis. On the other hand, late (<6months) patients complications and mortalities affected 256(62.4%) and 240(58.5%) of patients respectively; moreover, liver failure and sepsis were the most frequent causes of late mortalities in non-transplanted and transpla
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- Author
- Emad Hamdy Gad; Yasmin Kamel; Tahany Abdel-Hameed Salem; Mohammed Abdel-Hafez Ali; Ahmed Nabil Sallam
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)