About this document
Phase II Drug Metabolism Overview by Richard Lalisan is a document available to read on EtoBox.
This document provides an overview of Phase II drug metabolism focusing on glucuronidation and sulfation. It discusses the general properties of Phase II metabolism including conjugation reactions that yield metabolites with increased polarity and hydrophilicity. Common features are described such as the effect of conjugation on volume of distribution, clearance, and directing excretion. While conjugation often inactivates compounds, some conjugated metabolites are pharmacologically active. The document als
- Author
- Richard Lalisan
- Language
- EN