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Optogenetic Effects on Pituitary Behavior by Frontiers is a document available to read on EtoBox.
This study used optogenetics to enhance the activity of pituitary corticotroph cells in larval zebrafish immediately after the onset of stress. The researchers expressed a light-activated adenylyl cyclase (bPAC) specifically in corticotroph cells, allowing them to increase cAMP and calcium levels in the cells with blue light stimulation. They found that optogenetically enhancing corticotroph cell activity directly after stress onset was sufficient to rapidly modulate behaviors related to locomotion, avoidan
- Author
- Frontiers
- Language
- EN