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Urinary Toxicity after Treatment of High Risk Prostate Cancer using HDR Brachytherapy Boost by S.A. Gayadeen; E. Armstrong; J. Solano; D. Souza; T.S. Sullivan; H.A. Payne is a Agricultural and Biological Sciences article available to read on EtoBox.

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Introduction: Patients with chordoma of the skull base present a complex radiotherapy planning problem, which may benefit from advanced techniques. Patients and methods: Between 1996 and 2005, 9 adult patients with skull base or cervical spine chordoma were treated with conformal photon radiotherapy (CRT) (including forward-planned IMRT), following surgery. Data for 8 cases were available. The patients were re-planned with inverse-planned IMRT solutions, and the dosimetry compared with the conventional results to see if there were any significant differences. The Equivalent Uniform Dose (EUD) for tumour and normal tissues was used to compare plans. Minimum and maximum doses, volume coverage by the 95% isodose, and doses to organs at risk were recorded. Results: The mean and median GTV were 30.9 and 23 cm 3 ; the mean and median PTV were 120.8 and 114.1 cm 3 . In 5 cases, the PTV was greater than 100 cm 3 , and in 2 it reached approximately 200 cm 3 . The mean and median EUDs of the group were similar for the 2 planning methods means 92.5% and 93.6%; medians 97.9% and 94%, respectively. In 3 CRT cases the EUD fell below 90%, and in 2 IMRT significantly improved the dosimetry. In the

Who reads Urinary Toxicity after Treatment of High Risk Prostate Cancer using HDR Brachytherapy Boost?

Author

S.A. Gayadeen; E. Armstrong; J. Solano; D. Souza; T.S. Sullivan; H.A. Payne

Publisher

Elsevier Science; Springer; Elsevier ; Springer-Verlag; W. B. Saunders Co., Ltd.; Springer Verlag; Elsevier BV; Springer Science and Business Media LLC (ISSN 1433-2981)

Published

2007

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)