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Light emitting diode irradiation protect against the amyloid beta 25–35 induced apoptosis of PC12 cell in vitro by Rui Duan; Ling Zhu; Timon Cheng‐Yi Liu; Yan Li; Jiang Liu; Jianling Jiao; Xiaoyang Xu; Libo Yao; Songhao Liu is a Medicine article available to read on EtoBox.

What is Light emitting diode irradiation protect against the amyloid beta 25–35 induced apoptosis of PC12 cell in vitro about?

## Abstract ## Background and Objectives Whether light emitting diode (LED) irradiation has effects on “β‐amyloid (Aβ) induced apoptosis,” a leading hypothesis of the cause of Alzheimer's disease (AD), or not? ## Study Design/Materials and Methods Monolayer cell cultures of PC12 were subjected to Aβ or/and LED irradiation at various intensity. Cell apoptosis was confirmed by morphological criteria, DNA fragmentation assay, and FAScan flow cytometer assay. ## Results Treatment of the cells with LED irradiation significantly diminished Aβ induced apoptosis within 24 hours. ## Conclusions The LED irradiation, when utilized at power of 0.9 W/m^2^ and 60 minutes has significantly diminished Aβ induced apoptosis of PC12 cells. Lasers Surg. Med. 33:199–203, 2003. © 2003 Wiley‐Liss, Inc.

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Author
Rui Duan; Ling Zhu; Timon Cheng‐Yi Liu; Yan Li; Jiang Liu; Jianling Jiao; Xiaoyang Xu; Libo Yao; Songhao Liu
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)
Published
2003
Language
EN
Field
Medicine (Health Sciences)

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