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Topoisomerase enzymes (I and II) are crucial for preventing supertwisting and rotation of DNA during replication, facilitating strand separation. DNA replication involves several steps including strand unwinding, RNA primer formation, and synthesis of new DNA strands, with key enzymes like DNA polymerase and ligase playing vital roles. Additionally, mechanisms for DNA repair, such as excision and mismatch repair, are essential for maintaining genetic integrity.

Author

amo8163

Language

EN