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Cytomegalovirus in human abortion in Espı́rito Santo, Brazil by L.C Spano; P.R.M Vargas; F.S Ribeiro; J.P.G Leite; J.P Nascimento is a Medicine article available to read on EtoBox.

What is Cytomegalovirus in human abortion in Espı́rito Santo, Brazil about?

## Background: Despite the established implication of human cytomegalovirus (hcmv) in congenital infection, there are still conflicting reports regarding the association of hcmv with spontaneous abortion. viral antigens and nucleic acid were already described in tissues from abortions cases, but did not indicate hcmv pathogenical role. ## Objectives: (1) to access viral seroprevalence (total and igm antibodies) in pregnant, non-pregnant and in women in abortion process, (2) to evaluate if antigenemia assay can detect active infection in these populations, (3) to detect viral dna in peripheral leukocytes, and (4) in abortion tissues. ## Study design: Blood samples from 95 patients in abortion process and from two control groups (40 pregnant and 60 non-pregnant women) were obtained for determination of viral seroprevalence, for detection of antigen and viral dna by pcr from peripheral leukocytes. specimens obtained from 88 patients in abortion process, spontaneous or induced, were submitted to gb gene amplification (pcr and nested-pcr). ## Results: Viral seroprevalence were found in 97.3 with 2.5% of igm positive cases. antigenemia assay were negative in all cases, however, viral nuc

Who reads Cytomegalovirus in human abortion in Espı́rito Santo, Brazil?

Author

L.C Spano; P.R.M Vargas; F.S Ribeiro; J.P.G Leite; J.P Nascimento

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1386-6532)

Published

2002

Language

EN

Field

Medicine (Health Sciences)