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Bacterial diversity in primary infected root canals of a Chinese cohort: analysis of 16 S rDNA sequencing by Ziqiu Hu; Yonggang Xiang; Yanhong Wei; Xinsheng Gu; Weidong Leng; Lingyun Xia is a Dentistry article available to read on EtoBox.

What is Bacterial diversity in primary infected root canals of a Chinese cohort: analysis of 16 S rDNA sequencing about?

## Purpose To characterize the bacterial community in the primarily infected root canals. ## Methods A total of 13 samples were collected from the primarily infected root canals. 16 S rDNA sequencing was performed to define bacterial community. Taxonomic annotation, bacterial hierarchical structures, community richness and diversity, and inter-subject variability of the bacterial community in the root canal samples were analyzed. Gender, age, and duration of the toothache-specific bacterial community associated with the patient groups were analyzed. ## Results A total of 359 Species were annotated and identified in the whole study cohort. The Alpha diversity analysis showed that the species diversity and detection rate of the 13 samples were high, which reflected the authenticity of sequencing results. The Beta diversity analysis was used to compare the degree of difference between different root canal samples. The 13 samples were divided into two groups according to the results, group A was samples I1-I12, and group B was samples I13. The bacterial species of group A samples were analyzed with the clinical characteristics of patients, and it was found that gender, and duration spe

Who reads Bacterial diversity in primary infected root canals of a Chinese cohort: analysis of 16 S rDNA sequencing?

Author

Ziqiu Hu; Yonggang Xiang; Yanhong Wei; Xinsheng Gu; Weidong Leng; Lingyun Xia

Publisher

Springer Science and Business Media LLC

Published

2023

Field

Dentistry (Health Sciences)