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The study investigated the effect of methanolic leaf extract of Typha angustata in ameliorating phenothiazine-induced catatonia in Wistar rats. Phenothiazines like chlorpromazine are known to induce extrapyramidal side effects like tremors, muscular rigidity, and bradykinesia due to low dopamine, GABA, and high glutamate levels. The extract at a dose of 100 mg/kg significantly reduced these catatonic symptoms compared to the control group. The results suggest the methanolic extract of T. angustata has signi

Author
PharmaIntelligence
Language
EN