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The document outlines the preparation of p-nitro acetanilide, detailing its IUPAC name, solubility, melting point, and pharmaceutical use in synthesizing Acodazole for anti-neoplastic activity. The synthesis involves nitration of acetanilide using concentrated sulfuric and nitric acids through an electrophilic aromatic substitution mechanism. The procedure includes specific steps for mixing, cooling, and filtering to obtain the final product while addressing the reasons for each step in the process.
- Author
- Taha Abosrea
- Language
- EN