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Can I read Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS) on EtoBox?
Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS) by Wolfram E. Samlowski; Gordon A. Watson; Michael Wang; Ganesh Rao; Paul Klimo Jr; Kenneth Boucher; Dennis C. Shrieve; Randy L. Jensen is a Medicine article available to read on EtoBox.
What is Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS) about?
## Abstract ## BACKGROUND. Brain metastases are a frequent complication in advanced melanoma. A 3.6 to 4.1‐month median survival has been reported after treatment with whole brain radiotherapy. We performed a retrospective analysis of our institutional experience of multimodality treatment utilizing linear accelerator (Linac)‐based stereotactic radiosurgery (SRS). ## METHODS. Forty‐four melanoma patients with brain metastases underwent 66 SRS treatments for 156 metastatic foci between 1999 and 2004. Patients were treated with initial SRS if ≤5 brain metastases were present. All patients had Karnofsky Performance Status (KPS) ≥70, but 37 patients had active systemic metastases (Recursive Partition Analysis Class 2). Survival was calculated from the time of diagnosis of brain metastases. Minimum follow‐up was 1 year after SRS. The potential role of prognostic factors on survival was evaluated including age, sex, interval from initial diagnosis to brain metastases, surgical resection, addition of whole brain radiotherapy (WBRT), number of initial metastases treated, and number of SRS treatments using Cox univariate analysis. ## RESULTS. The median survival of melanoma patients with br
Who reads Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS)?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Wolfram E. Samlowski; Gordon A. Watson; Michael Wang; Ganesh Rao; Paul Klimo Jr; Kenneth Boucher; Dennis C. Shrieve; Randy L. Jensen
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)