Can I read Differential Regulation of Levels of Nicotinic Receptor Subunit Transcripts in Adult Sympathetic Neurons After Axotomy on EtoBox?

Differential Regulation of Levels of Nicotinic Receptor Subunit Transcripts in Adult Sympathetic Neurons After Axotomy by Yuefang Zhou; Evan Deneris; Richard E. Zigmond is a Neuroscience article available to read on EtoBox.

What is Differential Regulation of Levels of Nicotinic Receptor Subunit Transcripts in Adult Sympathetic Neurons After Axotomy about?

## Axotomy of adult peripheral neu- Y mRNA expression after axotomy. In the cases of rons produces decreases in the levels of transcripts these nicotinic receptor transcripts, however, similar for a number of proteins involved in synaptic transdecreases were seen in wild-type and LIF knockout mission. For example, tyrosine hydroxylase and neuanimals. Furthermore, administration of an antiseropeptide Y mRNA decrease in axotomized symparum to NGF in intact animals produced no changes thetic neurons in the superior cervical ganglion in transcript levels. On the other hand, providing ex-(SCG). In the present study, the effects of axotomy ogenous NGF to axotomized SCG in vivo or in explant on the expression of nicotinic receptor subunit trancultures partially prevented the decreases in the transcripts were examined in the SCG and the results were scripts for a3, a5, a7, and b4. These data indicate compared to those produced by deafferentation and that axotomy produces dramatic decreases in the exexplantation. Normally, neurons in the SCG express pression of several nicotinic receptor subunit tranfive different nicotinic subunits: a3, a5, a7, b2, and scripts, and that the molecular signa

Who reads Differential Regulation of Levels of Nicotinic Receptor Subunit Transcripts in Adult Sympathetic Neurons After Axotomy?

Author

Yuefang Zhou; Evan Deneris; Richard E. Zigmond

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-3034)

Published

1998

Language

EN

Field

Neuroscience (Life Sciences)