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Can I read Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon on EtoBox?
Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon by Henry J. Binder; Prasun Mehta is a Medicine article available to read on EtoBox.
What is Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon about?
Recent studies have established that mucosal butyrate stimulates electroneutral sodium-chloride (Na-C1) absorption in the distal colon of the rat and a model in which Na-hydrogen (H) and Cl-butyrate exchanges are coupled has been proposed as the mechanism ofbutyratedependent electroneutral Na-CI absorption. These studies were designed to examine butyrate-dependent electroneutral Na-C1 absorption in experimental conditions in which HCO3-dependent electroneutral Na-C1 absorption is inhibited: in Na-depleted (aldosteronetreated) animals and in the presence of increased mucosal cyclic adenosine monophosphate (AMP). Butyrate-dependent electroneutral Na-C1 absorption was markedly reduced in Na-depleted rats. In contrast, the inhibition of both net Na and net C1 absorption by 5 mM serosal theophylline was significantly less in butyrate-containing, HCO3-free Ringer solution than in butyrate-free-HCO3containing Ringer solution. These studies indicate that cyclic AMP does not inhibit butyrate-dependent electroneutral Na-C1 absorption and we propose that the mechanism of cyclic AMP inhibition of HCO3-dependent electroneutral Na-C1 absorption may be a result of its inhibition of C1-HCO3, not N
Who reads Characterization of butyrate-dependent electroneutral Na-Cl absorption in the rat distal colon?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Henry J. Binder; Prasun Mehta
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0031-6768)
- Published
- 1990
- Language
- EN
- Field
- Medicine (Life Sciences)